Delta Air Lines said it canceled about 625 flights Friday.
The Atlanta-based airline is thinning its operation due to the impact of the storm, including the need to de-ice planes.
Delta has waived certain change fees for passengers scheduled to fly Friday and Saturday who want to change their travel plans. The airline also advised travelers to check their flight status frequently and sign up for mobile or e-mail flight notifications.
Southwest Airlines, the second-largest carrier at Hartsfield-Jackson, said it canceled more than 60 flights and advised passengers to check their flight status.
De-icing throughout the day could cause delays of other flights, according to Southwest.
Dallas-based Southwest said passengers with reservations for Friday can rebook or travel standby without an additional charge.
Read more about airlines' flight cancellations on MyAJC.com.
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LEARN MORE: PREPARING FOR WINTER WEATHER
- Delta waives change fees for travelers ahead of snow threat
- Winter weather watch, warning and advisory: What's the difference?
- Metro Atlanta prepares for snow
- MyAJC.com weather page
Airlines have canceled some flights scheduled for Friday amid a winter storm in Atlanta.